Use of Anatomical Undercut in Adhesive Retained Orbital Prosthesis: An Alternative to Osseointegration to Improve Retention and Reduce Margin Gap.

Introduction: Poor retention, stability and margin gap due to excessive bone lose following surgery is one of the major problems of rehabilitation in orbital defect with adhesive retained orbital prosthesis. Presentation of Case: This clinical report describes a simplified technique for the fabrication of an adhesive retained silicone orbital prosthesis by proper evaluation and using of remaining tissue undercuts to achieve ideal fit and aesthetics in a patient who has severely loss orbital bone after the surgery. Discussion: Aesthetics will be compromised if the proper evaluation of remaining tissue and treatment plan is not done prior prosthetic rehabilitation. To solve this issue sometimes maxillofacial prosthodontist may have to think for implant retained facial prosthesis. This is also sometime not possible due to several factors such as peri-implantitis, hygiene practice and dose of radiation etc. Conclusion: Proper use of remaining anatomical undercuts can be an alternative way to overcome the issue.

In vitro antimicrobial effects of grape seed extract on peri-implantitis microflora in craniofacial implants

<p><b>OBJECTIVE</b>To determine the antimicrobial effects of grape seed on peri-implantitis microflora.</p><p><b>METHODS</b>The grape seed extract was tested against peri-implantitis microflora most commonly found in craniofacial implants including reference strains of Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), Candida albicans (C. albicans) and clinical strains of S. aureus, Klebsiella pneumonia (K. pneumonia) and Candida parapsilosis (C. parapsilosis) by disk diffusion test. Minimum inhibitory concentrations (MIC) and minimum cidal concentrations (MCC) were determined using modified agar dilution millpore method. The extract was further combined with polyethylene glycol and propylene glycol, and was tested for antimicrobial effects.</p><p><b>RESULTS</b>Grape seed extract showed positive inhibitory effects with S. aureus at MIC of 0.625 mg/mL and MCC of 1.25 mg/mL respectively. However the extracts showed minimal or no reactivity against strains of E. coli, K. pneumonia, C. parapsilosis and C. albicans. The use of grape seed extract in combination with polyethylene glycol and propylene glycol also showed dose dependent inhibitory effect on S. aureus.</p><p><b>CONCLUSIONS</b>The results of the study showed that grape seed has potential antimicrobial effects which can be further studied and developed to be used in the treatment of infected skin-abutment interface of craniofacial implants.</p>

Determination of oral microflora in irradiated ocular deformed children.

Children with a retinoblastoma usually have enucleation of eye contents and undergo radiation therapy. In this group of children a slight deformation in facial growth is exhibited on the operated side. The radiation affects the oral microflora. This study was conducted to investigate the oral microflora in this group of patients compared to normal children. Nineteen children, ages 4-15 years, were tested for oral microflora by culture. A control group was comprised of 20 normal healthy children from a primary school in Bangkok, Thailand. Paraffin-stimulated whole saliva was collected and cultured for the presence of mutans streptococci, lactobacilli and Candida species. The isolation frequencies and abundances of lactobacilli and Candida species in saliva samples of irradiated children were significantly greater than healthy children. The mutans streptococci counts were significantly different from healthy controls. Radiation therapy may have had some influence on the oral ecology of these patients, so had a higher risk of caries and candidiasis than the healthy controls. Therefore, comprehensive preventive measures should be taken in these children.